Inhibited fragmentation of mAbs in buffered ionic liquids.
نویسندگان
چکیده
We thoroughly investigated the biological, structural and chemical stability of epidermal growth factor receptor monoclonal antibody (EGFR mAb) using choline-based buffered ionic liquids (BILs). The results demonstrated substantially enhanced stabilities in our BILs, indicating their huge promise as real-world green biological buffers for antibody storage and transportation.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 38 شماره
صفحات -
تاریخ انتشار 2015